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In a Phase 2 clinical trial published in the New England Journal of Medicine (Jastreboff et al., 2023), participants using retatrutide experienced up to 24% reduction in body weight over 48 weeks, significantly outperforming earlier GLP-1 agents
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Their potential to lower urate levels has garnered attention, providing a rich field for further exploration in the quest for effective hyperuricemia management [98, 99, 100]
Further Dosage Adjustments: After a minimum of four weeks at each dose level, your provider may adjust your dose upward based on your response and tolerance
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