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Historically, the liver has been acknowledged as the main location where metformin reduces glucose levels, however, there is increasing evidence suggesting that the gastrointestinal tract also plays a significant role in its action

The relationship between GLP-1 therapy and joint pain relief appears to be multifactorial rather than a direct pharmacological effect on joint tissues

A 30-min permeability test for SF and EBA markers performed after the 24-h nanocarrier permeability assays confirmed that the integrity of the BBB models was preserved and the nanocarriers had no barrier damaging effect (Table S2)

Patients who value continuity of care will feel like they are starting over with each provider exchange