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While no officially approved human dosing exists, community experience and extrapolation from animal research provide useful guidance

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Regulation of research subjects mesenchymal stem cell functions by an autocrine loop [PMID: 20964598] Laboratory literature summary: Regulation of research subjects mesenchymal stem cell functions by an autocrine loop involving NAD+ release and P2Y11-mediated signaling

In 1996, the Department of Pharmacology at the University of Arizona conducted a phase 1 clinical trial on 3 men to investigate the direct effects of Melanotan 2 in healthy humans