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It supports blood pressure regulation with mild hypotensive effects by promoting autonomic balance
Genetics of diabetic nephropathy in type 2 DM: candidate gene analysis for the pathogenic role of inflammation
It plays a critical role in detoxification, immune defense, and protecting against oxidative damage
Specifically, in cells, lysine is sequentially catalyzed by enzymes including AASS, ALDH7A1, AADA, DHTKD1 to generate glutaryl-CoA, which is then catalyzed by crotonyl-CoA-producing enzyme glutaryl-CoA dehydrogenase (GCDH) to produce crotonyl-CoA, that is, the precursor for the crotonylation of histones and non-histone proteins [37]
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