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(Simple Explanation) Oxidative stress occurs when there is an imbalance between: Free radicals (unstable molecules that damage cells) AND Antioxidants (your bodys defense system) Think of it like this: Oxidative stress = internal rusting of your cells When this process goes unchecked, it can damage: brain cells mitochondria (your energy production centers) blood vessels immune function Why This Matters in Long COVID Emerging research suggests that oxidative stress plays a central role in Long COVID (PASC)

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Retatrutide can cause more serious stomach reactions than placebo, so it is not recommended for people with serious gastrointestinal illness, like gastroparesis

The large 2025 meta-analysis quantified this as approximately 63% higher gastrointestinal adverse event rates compared with placebo, and gallbladder disorders were about 26% higher