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A few GLP-1 agonists currently in phase 3 trials are higher-dose injectable semaglutide 7.2 mg (Novo Nordisk), oral semaglutide 50 mg (Novo Nordisk) and orforglipron (Eli Lilly)
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Maintaining a consistent scheduletaking levothyroxine on an empty stomach 3060 minutes before food or other medicationsminimizes any theoretical effect, and PlexusDx injection avoids oral absorption concerns entirely
These studies, which followed thousands of patients over several years, did not demonstrate an increased incidence of fractures compared to placebo or other diabetes treatments
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