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Concepts in clinical pharmacokinetics
Baseline measurements obtained from the participants determined that 64% of the participants were male, while the mean age was 58 years old, average diabetes duration was approximaely 9 years, the mean HbA1c was recorded at 8.4%, as well as an average body weight of 105.7 kg
Higher doses of dulaglutide (3.0 mg and 4.5 mg) [29] have also received marketing approval for treatment of type 2 diabetes, while application for a label extension of semaglutide at the dose of 2.0 mg [30] has been submitted to the US FDA and has recently received a positive recommendation by the EMA
Novo Nordisk has flagged growing generic competition in markets including India as a potential drag on its international business in 2026, highlighting rising pressure on branded obesity and diabetes therapies as semaglutide loses exclusivity in several countries
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