Currently, multiple phase 3 trials with oral semaglutide and orforglipron are ongoing for different populations (NCT05803421), while another oral GLP-1 RA (CT-996) is in early phase clinical trials (Table 1)
Serge Jabbour et al., DURATION-8 Randomized Controlled Trial 104-Week Results - Once-Weekly Exenatide (ExQW) plus Once-Daily Dapagliflozin (DAPA) vs
Prior authorization is common, and insurers may require proof that cheaper alternatives (e.g., metformin) didnt work when used to treat diabetes
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