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As you lose weight, your metabolism changes, and your body may require an adjustment in dosage or a shift in nutritional strategy

GLP-1 helps regulate blood sugar and digestion

Association between weight reduction achieved with tirzepatide and health-related quality of life in people with overweight or obesity

Besides their special organization in lipid domains (lipid rafts) of the membrane lipid bilayers, some sphingolipids, e.g., ceramides, sphingosine, and sphingosine-1-phosphate have been described to function as lipid-derived second messengers mainly regulating fundamental cellular pathways such as apoptosis and differentiation [119, 120]