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The Pyo study demonstrated that AHK-Cu increased DPC proliferation at concentrations ranging from picomolar to nanomolar remarkably low concentrations suggesting high biological potency for this specific cell type
RBDs from Bat CoV RaTG13, Bat CoV SHC014, Bat CoV Rs4081, Bat CoV RmYN02, Bat CoV Rf1, Bat CoV WIV1, Pangolin CoV Pang17, and SARS-CoV-2 were expressed on SpyTag proteins, which were then fused to one SpyCatcher protein with multiple domains, leading to the generation of the mosaic-8b nanoparticle vaccine [141]
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