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However, the broad distribution of GLP-1 receptors across various tissues, such as the pancreas, lungs, kidneys, central nervous system, cardiovascular system, gastrointestinal tract, skin, and thyroid gland, has raised concerns about the potential impact of GLP-1 RAs on cancer development and progression [23]
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Canadas Drug Agency recommended that Wegovy, part of the semaglutide group of medications, be available for public reimbursement, provided certain conditions are met for chronic weight management. According to the recommendations, patients eligible for the proposed coverage would have a body mass index (BMI) of 27 kilograms per square metre or greater and have a pre-existing cardiovascular disease
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