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This seems counterintuitive since tirzepatide activates an additional receptor, but the GIP component appears to have a moderating effect on GLP-1 induced nausea
87 , e0054421 (2021)
The peptide itself is a modified alpha-melanocyte-stimulating hormone analog (alpha-MSH) composed of a precise amino acid sequence that is irreversibly damaged by mechanical agitation, temperature excursions above 8C after reconstitution, or bacterial contamination introduced during mixing
The biggest limitation is that the study cannot prove cause and effect, Sudhakaran says
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