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An imbalance between excitatory and inhibitory neurotransmitters in amyotrophic lateral sclerosis revealed by use of 3-T proton magnetic resonance spectroscopy
Studies in the FOXO4-DRI peptide suggest it may boost natural processes while possibly also eliminating dysfunctional cells
Notably, these macroscale mechanical property changes with high dynamic loading were non-recoverable after 1000 s of rest at 0% strain, indicating that permanent macroscale mechanical alteration was present in these groups and that this loading protocol was indeed fatigue loading the tendons (Figure S4e,f)
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