You may notice you are timing your supplement correctly when you experience: Better stamina during workouts Quicker recovery A slight increase in daily energy Improved ability to stay lean while training Gradual reduction in stubborn fat If you feel a noticeable lift before your workout and better endurance during it, your timing is working
Okamoto N, Yoshino K, Kitagawa S, Fujii R, Hamada S, Ikenouchi A, et al
These include capsaicin (reduces the level of a pain transmitter called Substance P), SAMe or S-adenosylmethionine (an endogenous compound that stimulates cartilage production), and anthocyanidins (an antioxidant that prevent the degradation of collagen)
Baseline characteristics and blood samples were collected at d 0, 1, 2, 3, 7, 28, 56, 84 and 112 after the intervention