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(NIH) In adults over 55 with type-2 diabetes, GSH supplementation improved glutathione stores and reduced DNA oxidative damage (8-OHdG) while lowering HbA1c.(NIH) However, short-term trials (4 weeks) in healthy adults showed no measurable change in blood GSH, highlighting absorption variability
The IOM has set the UL for selenium for adults at 400 micrograms per day
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R This variant has been associated with increased breast cancer risk in some populations, possibly through reduced sulfation and inactivation of catechol estrogens and environmental estrogens
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