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In addition, the mode of action of gabapentinoids has been suggested to involve inhibition of descending serotonergic facilitation, stimulation of descending inhibition, anti-inflammatory actions, and influence on the affective component of pain [23]
Across the major obesity and diabetes programmes, escalation protocols were used before reaching maintenance doses, with studies continuing for up to 68 weeks in obesity research
Taste preference was calculated as Kool-Aid/total fluid consumed
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