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doi: 10.1016/j.talanta.2008.10.046
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This broad gene expression effect combined with telomerase activation and melatonin restoration positions epitalon as a multi-mechanism anti-aging intervention that addresses several hallmarks of aging simultaneously
IL-1 is known to directly induce fatigue and malaise through stimulating the hypothalamic-pituitary-adrenal axis and inflammatory signaling pathways in the central nervous system (CNS) [35, 36]
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