Le Thuc O, Stobbe K, Cansell C, Nahon JL, Blondeau N, Rovre C (2017) Hypothalamic inflammation and Energy Balance Disruptions: spotlight on Chemokines
Biotin (White Liquid Small Vial) - 1g Role: Also known as Vitamin H, Biotin is essential for skin, hair, and nail health
What they found (summary): MC1R: melanogenesis, pigmentation, anti-inflammation MC2R: ACTH receptor in the adrenals (Melanotan II does not act) MC3R: energy, cardiovascular function, anti-inflammation MC4R: appetite (central control), sexual function, autonomic regulation MC5R: exocrine glands (sebaceous, lacrimal, salivary) Mutations in MC4R are the most common monogenic cause of obesity in humans Why it matters: Cones review article is the reference article for all of melanocortin pharmacology
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