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The peptide activates PI3K/Akt signaling that translocates GLUT4 glucose transporters independent of insulin, bypassing normal feedback loops

Nature New Biology 243(124):85-87. [doi.org]

Collectively, these data argue for biomarker-guided, context-specific modulation of microbial pathways (e.g., SCFAs abundance, choline intake, barrier-stabilizing metabolites) to complement standard PCa therapies

Berg JM, Bhalla N, Bourne PE, Chalfie M, Drubin DG, Fraser JS, Greider CW, Hendricks M, Jones C, Kiley R, King S, Kirschner MW, Krumholz HM , Lehmann R, Leptin M, Pulverer B, Rosenzweig B, Spiro JE, Stebbins M, Strasser C, Swaminathan S, Turner P, Vale RD, VijayRaghavan K, Wolberger C