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Elderly Patients Older adults may be more sensitive to side effects, particularly: Dehydration from gastrointestinal effects Falls risk from dizziness or low blood sugar Drug interactions with multiple medications Need for slower dose escalation Women of Childbearing Age Important considerations include: Both medications should be stopped 2 months before planned pregnancy Weight loss may improve fertility in some women Reliable contraception recommended during treatment Not recommended during breastfeeding The Future of Weight Loss Medications The field of obesity medicine continues to evolve rapidly
Glutathione is synthesized in two sequential enzymatic reactions: glutamate cysteine ligase (GCL) catalyzes the first, rate-limiting step, and glutathione synthetase couples -glutamylcysteine to glycine in the last step [13]
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