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Two randomized control clinical trials reported conflicting effects on bone mineral content (BMC) and bone mineral density (BMD): one trial demonstrated preservation of BMC with GLP-1 use, while the other found no significant difference in BMC or BMD between treatment and control groups

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Subgroup analysis and other analysis Appendix: Table S3 shows the subgroup analysis results

3 Results 3.1 Patient samples The hypothyroidism sample (N = 40) included the following co-occurring diagnoses and conditions (N = 21) made at least 1 year before starting L-carnitine supplementation in the study: hypertension (N = 6), type 2 diabetes (N = 6), sleep apnea managed with CPAP treatment (N = 3), Sjgrens Syndrome (N = 2), vitiligo (N = 2), hypercholesteremia (N = 2), menopausal symptoms (N = 2), asthma (N = 1), celiac sprue (N =1), and Menieres Disease (N = 1)