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NNMT plays a key role in metabolic dysfunction, and its inhibition has been shown to reverse obesity-related changes in adipose tissue. Kraus et al., Cell Metabolism How 5-Amino-1MQ Works The primary mechanism behind 5-Amino-1MQ lies in its ability to inhibit nicotinamide N-methyltransferase (NNMT) an enzyme that is often overexpressed in fat cells, cancer cells, and aging tissues
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The drug's lack of efficacy on weight loss may raise questions of what the fuss is all about, but there is just one obvious problem: the clinical trials tested a fat-burning pill and allegedly at much lower doses than that given to the footballers
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