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For many women, Prozac provides relief from the debilitating symptoms of PMDD, allowing them to maintain their quality of life
Possible side effects may include abdominal cramping, loose stools, and changes in bowel movements
Subsequent assay studies indicated that (R)-3-amino-1-(2-benzoyl-1,2-diazepan-1-yl)-4-(2,4,5-trifluorophenyl) butan-1-one (40) possesses strong in vitro activity, favorable selectivity, and in vivo efficacy in mouse models (Figure 6)
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