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GLP-1 receptors are present in various tissues throughout the body, including pancreatic beta cells, the gastrointestinal tract, and the brain
Absolute contraindications to phentermine, regardless of GLP-1 status: Uncontrolled hypertension History of coronary artery disease or heart failure Uncontrolled hyperthyroidism Glaucoma History of substance use disorder (phentermine is Schedule IV) Use within 14 days of MAO inhibitors Pregnancy or planning pregnancy Age over 65 (relative contraindication) The GLP-1 alone may still be appropriate in many of these scenarios
Ethics statement The studies involving human participants were reviewed and approved by This research was approved by the Institutional Review Board (IRB
It's crucial for fat metabolism and cellular signaling
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