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They identified a protein called Med14part of a larger protein complex called Mediatorthat was enabling the GLP-1-dependent changes in gene expression that lead to pancreatic health benefits
Kliers, et al., 'Phase 3 Trial of Semaglutide in Metabolic Dysfunction-Associated Steatohepatitis', N
Researchers studied how it interacts with the ghrelin or growth-hormone secretagogue receptor, often abbreviated GHSR, and how that interaction affects measured endocrine responses in specific experimental systems
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