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In a head-to-head trial against semaglutide (the SURPASS-2 trial), tirzepatide produced significantly greater weight loss, with participants taking the highest dose of tirzepatide losing an average of 11.2 kg (24.7 lbs), compared to 5.7 kg (12.5 lbs) for those taking semaglutide 1 mg
If you experience low mood, thoughts of self-harm, or suicidal thoughts, seek urgent medical help contact your GP, call NHS 111, or in an emergency call 999 Patients are encouraged to ask their doctor about the current evidence base, the distinction between trial data and licensed use, and what support will be available if side effects occur
Women with hormone-specific needs
Weight loss for Trulicity is typically more modest than Ozempic
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