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Who Should Not Use Sermorelin Like any growth hormone-stimulating therapy, Sermorelin is contraindicated in patients with active malignancy or a personal history of certain cancers, because anything that drives GH/IGF-1 production has theoretical risk in those settings
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A variety of neurotransmitter pathways, as well as various peripheral feedback signals, regulate the secretion of GH by acting directly on the anterior pituitary gland and/or by regulating the release of GHRH or somatostatin in the hypothalamus (Zadik et al., 1985)
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