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Peroxynitrite can induce mitochondrial dysfunction through a calcium-dependent process, which leads to chondrocyte apoptosis mediated by calpain (Whiteman et al., 2004)
On January 24, 2024, the Judicial Panel on Multidistrict Litigation (JPML) heard arguments from both attorneys for plaintiffs and attorneys for the drug makers concerning the formation of a new multidistrict litigation (MDL) to house the hundreds and thousands of lawsuits that will follow in the coming months and years
Data from that study were published in NEJM
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