surmount-1 tirzepatide weight loss nondiabetic trial SURMOUNT 1 // Three-Year Obesty & Diabetes Prevention Outcomes Unlock the Secret to Sustainable

Ozempic was resumed, and with the exception of a 3-week interruption due to his roommate accidentally moving the Ozempic to the freezer, he remains on it as of February 2025, with a weight loss of 25 lb/11.3 kg (6.5%) since resuming it

The timeline for tirzepatide to work depends on consistent weekly dosing far more than on what time of day you inject

At cash list, compounded tirzepatide via telehealth runs roughly 50% to 75% cheaper than brand Zepbound at CVS: CVS Zepbound (autoinjector pen, cash): $1,059 to $1,200 per month CVS Zepbound (with GoodRx): roughly $970 to $1,100 per month LillyDirect Zepbound 5 mg vial: $499 per month Telehealth compounded tirzepatide: $299 to $499 per month For commercially insured patients with Zepbound coverage and the Lilly savings card, the $25 copay beats every cash alternative

For diabetes management, providers assess HbA1c trends, fasting and postprandial glucose patterns from self-monitoring or continuous glucose monitoring data, and time-in-range metrics when available