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Those with surgically confirmed recurrence had increased odds of adenomyosis as detected by ultrasound compared to controls (univariate OR 4.40 [1.5212.73], p value 0.006) (Table 3)
Most patients starting with normal b12 levels and no significant risk factors do not require supplementation
The maximum dose is 15 mg, supported by SURPASS2 trial data showing the greatest reductions in A1C (2.30%) and body weight (11.2 kg or ~24.7 lb)
It modulates GABA and serotonin systems involved in pain processing
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