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The treatment must be authorized for sale by Health Canada, which means they have to submit multiple studies to prove bioequivalence confirming it delivers the exact same amount of medicine into the body at the exact same rate, guaranteeing identical safety and effectiveness
For patients with moderate renal impairment (eGFR greater than or equal to 30 mL/min/1.73 m2 to less than 45 mL/min/1.73 m2), the dose of JANUVIA is 50 mg once daily
L-carnitine is sold as a food supplement for the general adult population
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