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But Americans with low incomes or who lack comprehensive employer health insurance coverage often struggle to obtain the medications

Clinical trials and real-world studies consistently show that gastrointestinal symptomsnausea, vomiting, diarrhea and constipationare the most common side effects of GLP-1 receptor agonists.Harvard Health+3Nature+3PMC+3 In obesity trials in particular, constipation often shows up more frequently than it does in type 2 diabetes trials.Taylor & Francis Online+1 As a nutritionist who works every day with people struggling with IBS, chronic constipation, bloating and other functional digestive issues, Im seeing more and more clients who are also using GLP-1 medications

Gastrointestinal symptoms are the most frequent side effects, affecting approximately 40% of patients during the initial titration phase

Weight loss varies depending on individual factors such as starting weight, adherence to the treatment plan, and lifestyle choices