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At 26 weeks, mean percentage reductions in weight (the primary outcome) were 6.0 Percentage to 10.8 Percentage in the cagrilintide groups compared with 9.0 Percentage in the liraglutide group, and 3.0 Percentage with placebo [9]
The freeze-thaw cycle destroys peptide structure and eliminates therapeutic activity
It does not alter insulin sensitivity
Prediction of de novo hepatocellular carcinoma (HCC) in these patients is particularly important considering limited medical resources and relatively lower incidence of HCC compared with those treated for 5 years and were not diagnosed with HCC during the first 5 years of therapy were selected, respectively
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