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Also, individuals with pre-existing thyroid disorders are considered more susceptible to potential adverse effects of excess iodine (either hypo or hyperthyroidism) [5, 22]

To validate the role of KRT32 in cellular proliferation, immortalized keratinocytes cell lines (Ker-CT), were used to build the cell models with overexpression and knockdown of KRT32, as depicted in Supplementary Fig

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Under these uncontrolled conditions, the concentrations of ROS exceed the capacity of local antioxidant molecules neutralize them (29, 112, 115, 150), resulting in a buildup of ROS O and H 2 O 2 , and also malondialdehyde, at the site of the ovary and in follicular fluid and peritoneal fluid (29, 103, 105, 106, 108, 111, 112)