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Variations in the GLP1R gene (such as rs6923761) affect receptor sensitivity, meaning some individuals naturally tolerate GLP-1 activation better than others
It also means the drowsiness effect will hit you during your waking hours, which most patients find disruptive
And patients with medical conditions like diabetes and heart disease can still get coverage for weight-loss drugs through IBX
Initial results were published in the New England Journal of Medicine in March showing a 14% reduction in MACE
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