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However, succinate has been also regarded as a detrimental metabolite in ischemia-reperfusion injury due to its rapid oxidation at the onset of tissue reperfusion, which drives reactive oxygen species generation and necrotic cell death 58
M.MezS.del Carmen RecioM.SchinellaG.RiosJ
34,114 During the fasting state, glucagon promotes gluconeogenesis in hepatocytes by inducing glycogen breakdown
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