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Second, the -glutamylcysteine product is coupled to glycine via GSH synthetase (GSS) to produce GSH or reduced GSH ( via GSH-dependent peroxidase-catalyzed reactions ( T2DM is a chronic metabolic disease characterized by hyperglycemia, prolonged elevated levels of glucose, and insulin resistance
Malnourishment, eating disorders, and cachexia (muscle wasting) can also increase the risk of liver injury following overdose (Ferner 2011)
Zhang L, Zhang W, Xu H, Liu K
Shao M, Liang H, Xu G, Zhu J, Li S, Ren M
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