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It varies between people
[48] A 10 mg dose has been shown to be effective in reducing insulin resistance, with a reduction of around 8% from baseline, measured using HOMA2-IR (computed with fasting insulin)
Intake of higher doses doesnt appear to be associated with detrimental health problems.2 The VNDPG recommends the following B12 guidance2: All vegetarians, regardless of type, should periodically be screened for B12 deficiency, using either methylmalonic acid (MMA) or TCII (transcobalamin) assessment
A theoretical model of gamma-globulin catabolism
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