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Disadvantages are low bioavailability, poor stability, and obvious sulfur odor
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Ludvik B, Giorgino F, Jdar E et al (2021) Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial
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