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ASS1 expression has been reported to be decreased or even abolished in many cancers (Dillon et al., 2004), especially in malignant melanoma (Feun et al., 2012), HCC (Delage et al., 2010), and prostate cancer (Kim et al., 2009), which are thought of as arginine-auxotrophic cancers because of the inability to synthesize arginine and resulting susceptibility to arginine-deprivation therapy
Hiking Red Rock Canyon or Lake Mead in July without serious hydration can be risky
GLP-1RAs activate GLP-1R similarly to GLP-1, but they are resistant to the activity of DPP-4
doi: 10.3945/an.116.012716 2
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