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Retatrutide works like other weight loss and type 2 diabetes medications, but what makes it different is that it can target three receptors (triple agonist) at once: Gastric inhibitory polypeptide receptor (GIP) Glucagon-like peptide-1 receptor (GLP-1) Glucagon receptors (GCG) This unique triple-action may make it more effective than GLP-1 and GLP-1/GIP medications

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