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In cultured cardiomyocytes, DOX concentrates in mitochondria, increasing mitochondrial iron deposition and ROS levels, and dexrazoxane has demonstrated efficacy in reversing DOX-induced cardiomyopathy by lowering mitochondrial iron levels
NSL literature pointer PMID 15574960 L-Carnitine laboratory index [PMID: 15574960] National Science Labs indexing note for PMID 15574960: review the PubMed methods, models, and limitations before citing
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