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In addition, some sHSPs, such as HSPB1/HSP27 and HSPB5, can be phosphorylated through kinase pathways, including the p38/MK2 pathway, which may regulate their chaperone activity, cytoskeletal interactions, and involvement in autophagy-related clearance of damaged cellular components (Ungelenk et al., 2016
a Barplot displaying the effect sizes and associated p -values from generalized linear models (GLMs) predicting individual metabolite levels (log 10 -transformed) based on fecal samples
doi: 10.1021/pr500907d 61 LamegoIMarquesMPDuarteIFMartinsASOliveiraHGilAM
To overcome these limitations, we previously developed a fluorescent real-time thiol tracer (FreSHtracer) that monitors cellular levels of glutathione (GSH), which are known to be closely associated with stem cell function
