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The search details are shown in Supplementary Table 1, meantime the inclusion criteria were as follows: (i) patients with PCOS, (ii) patients with the treatment of carnitine supplementation, (iii) patients with body weight information, (iv) patients with exact doses and durations of carnitine supplementation, and (v) patients with the control group
A multicenter, randomized, double-blind, multiple dose-escalation study showed that after 4 weeks of treatment of PEX-168 with different doses, the weight decreased by -0.8-1.8kg
The medication has helped me naturally change my eating habitsI feel satisfied with smaller portions and no longer have the urge to overeat
Conversely, a shot-gun approach to eating more fiber can lead to a microbiome composition that produces fewer SCFAs, reducing PYY levels and contributing to overeating
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