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In brief, approximately 2 10 6 cells from each sample were incubated with the reaction mixture at room temperature for 2 min in the dark

Interestingly, they are involved in microglial response pathways, which supports a role for CNS immune response and neuroinflammation in the pathophysiology of AD ( Beta-amyloid accumulation in the brain is currently the most commonly accepted hypothesis for the onset of AD pathology, but findings that beta-amyloid is also found in the brain of healthy older adults and that the association between beta-amyloid load and dementia symptoms lessens with age support the contribution of other factors, such as tau accumulation, inflammation, as well as metabolic and cardiovascular factors (106, 112)

Glutathione and liver health: insights from clinical practice

Neurochem Int 142:104926