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The methylcobalamin component is generally safe in renal impairment, though accumulation of cobalt has been reported in patients with severe renal dysfunction receiving high doses of vitamin B12
For a deeper dive into compounded semaglutide refrigeration requirements, see our dedicated article
doi:10.1016/S0006-2952(99)00166-5
Copper is only required in trace amounts by the body, and too much copper buildup could theoretically cause nausea, abdominal pain, tiredness, liver damage, and neurological effects
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