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"For Lilly, this is surely progress, but for many patients, at least in the near term, Im not so sure," Alliance for Pharmacy Compounding CEO Scott Brunner said in a statement
However, for multi-dose vials (which most semaglutide vials are), bacteriostatic water is required
A 2024 analysis found that each year of delay in starting GLP-1 therapy for patients with obesity and prediabetes was associated with a 12% increased risk of progression to Type 2 diabetes (Wilding et al., Lancet Diabetes & Endocrinology, 2024)
Common eligibility variables include BMI thresholds, presence or absence of type 2 diabetes, geographic proximity to the trial site, and exclusion criteria around prior GLP-1 use or specific medical history
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