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Metabolic immune checkpoint ecto-5-nucleotidase (CD73) significantly inhibits the function of anti-tumor T cells and increases the activity of immunosuppressive cells by regulating the imbalance of extracellular adenosine (ADO), while multifunctional Au@Cu 2-x Se nanoparticles (ACS NPs) significantly inhibit the expression of CD73 thereby reducing ADO production, lowering ADO-driven immunosuppression and enhancing the infiltration and activity of anti-tumor T cells in tumors (240)

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La vitamine C, quant elle, stimule la production de collagne, ce qui attnue les ridules