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Its cognitive-enhancing effects build over days to weeks through neuroplasticity mechanismsBDNF upregulation, synaptic remodeling, and gene expression changes

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In the intestines, butyrate plays a regulatory role on the transepithelial fluid transport, ameliorates mucosal inflammation and oxidative status, reinforces the epithelial defense barrier, and modulates visceral sensitivity and intestinal motility (Canani et al., 2011)

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