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The implication is that there is a neuron population nucleus tractus solitarius GLP-1R neurons that can decrease appetite and cause weight loss without making individuals feel sick and so we hope that this finding will lead to the development of more selective weight loss drugs. We all know that nausea is almost always accompanied by appetite loss, and so we thought that the GLP-1 drugs may suppress appetite simply by making individuals feel nauseated
All known effects discussed here are derived from laboratory models, and careful interpretation is essential when considering relevance to human biology
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